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Issues with poor flowing CBD Isolate? We can solve that!

Tag Archive: Granulation Experts

  1. Alexanderwerk Experts support Top Hands-On Training Event in the US (April 20 – 22, 2021)

    Comentarios desactivados en Alexanderwerk Experts support Top Hands-On Training Event in the US (April 20 – 22, 2021)

    Natoli

    Our partner Natoli Scientific organizes a 3-day-seminar in Telford (PA) and our experts from Alexanderwerk Inc. will support this top hands-on training event. The seminar will take place at the Natoli Scientific Center in Telford (April 20 – 22, 2021). Hurry up to get registered for this event as seats are limited.

    Natoli is well-known for their tablet presses, tooling, and also for their global reach in training formulators and operators. The partnership with Natoli began years ago and we are happy, that our colleague Al Friedrich, National Sales Engineer Alexanderwerk Inc., will support Robert Sedlock and his team at Natoli in Telford (PA, USA). Mr. Friedrich will do the lectures on Dry Granulation and Milling.

    And don’t miss the chance to visit our lab in Montgomeryville, which just a 20 minute drive from Telford!

    The organizer’s website can be reached here. Please contact Natoli’s team for further Covid-19 and implemented hygienic concepts and requirements.

    A flyer for the seminar can be downloaded from Natoli’s website.

  2. Alexanderwerk supports a tableting seminar organized by Romaco in Feixiang, P.R. China on April 10th and 11th, 2021.

    Comentarios desactivados en Alexanderwerk supports a tableting seminar organized by Romaco in Feixiang, P.R. China on April 10th and 11th, 2021.

    Alexanderwerk specialist Mrs. Dora Huang will support a tableting seminar organized by Romaco in Feixiang, P.R. China on April 10th and 11th, 2021.

    Once again, Alexanderwerk shows its commitment to this important market by supporting local pharmaceutical companies in giving them insights in the technology of dry granulation. Dora Huang, who joined our Chinese office earlier in February this year, can use her vast expertise in dry granulation combined with Alexanderwerk’s leading compaction and granulation technology and provide best technical solutions to our Chinese customers and partners.

    Alexanderwerk will also provide technical trainings for your staff! Get in contact and speak to our partners and colleagues all around the world.

  3. Alexanderwerk Experts support Top Hands-On Training Event held at Natoli PA (April 20 – 22, 2021)

    Comentarios desactivados en Alexanderwerk Experts support Top Hands-On Training Event held at Natoli PA (April 20 – 22, 2021)

    Natoli hands on training

    Our partner Natoli Scientific is organizing another 3-day-seminar in Telford (PA) and our experts from Alexanderwerk Inc. will support this top hands-on training event. The seminar will take place at the Natoli Scientific Center in Telford (February 16 – 18, 2021). Hurry up to get registered for this event as seats are limited.

    Natoli is well-known for their tablet presses, their toolings and also for their global reach in trainings. The partnership with Natoli began years ago and we are happy, that our colleague Al Friedrich, National Sales Engineer Alexanderwerk Inc., will support Robert Sedlock and his team at Natoli in Telford (PA, USA). Mr. Friedrich will do the lectures on Dry Granulation and Milling.

    The organizer’s website can be reached here. Please contact Natoli’s team for further requirements due to Covid-19 and implemented hygienic concepts.

    A flyer for the seminar can be downloaded from Natoli’s website.

    This course provides comprehensive insight into the tablet development process and scale-up techniques with the same unique classroom and hands-on training you have come to expect from Natoli. The 3-day training course incorporates open discussions, one-on-one consultations, Q&A, and live demonstrations. Light breakfasts and full lunches will be provided.

    COURSE REVIEW

    Learning OBJECTIVES:

    Participants of this training course will finish with an understanding of these concepts:

    » Tablet design

    » Tablet compression with scale-up

    » Blending

    » Granulation (roller compression, high shear, fluid bed)

    » Compaction emulation

    » Tablet coating

    » Excipient selection

    » Formulation development strategies

     

    Who Should ATTEND?

    This course is designed for those involved in tablet compression Research & Development including:

    » Compounding Pharmacists

    » Technology Transfer Scientists

    » Process and Validation Engineers

    » Formulation Scientists

    » Research Associates

    Early Bird pricing is available through April 9th

  4. Online Training on February, 8th was a great success

    Comentarios desactivados en Online Training on February, 8th was a great success

    Natoli

    Our partner Natoli organized an online training session on February 8, 2021 (10:00 AM – 11:30 AM EST) with focus on “Dry Granulation Formulation & Tableting Techniques” and Alexanderwerk supported this event. Almost 400 participants registered for this online seminar, which was a huge success!

    Did you miss this event? No problem! Our partner made the seminar available to you online!

  5. 5 common questions about roller compaction and dry granulation e-book released

    Comentarios desactivados en 5 common questions about roller compaction and dry granulation e-book released

    WP 200

    At Alexanderwerk, we are the world’s leading provider of dry compaction and granulation solutions. We offer high-quality standard and custom machines that support critical processing applications in the chemical, pharmaceutical, food, life science, and nuclear fields. We just published an eBook in which we provide answers to five of the most commonly asked questions regarding the roller compaction process, including how it works, what advantages it offers, what the significance of parameter controls is, what a typical roller compaction operation and system look like, and what products it accommodates.

    1. What is the science behind powder processing during roller compaction operations?
    2. What powder processing techniques are there and what advantages does roller compaction have over other powder processing techniques and technologies?
    3. What are the significant control parameters in roller compaction operations?
    4. What does a typical roller compaction operation and system look like?
    5. What products can be compacted, and how is material flow addressed?

    Please check out the answers in our ebook using this link: https://alexanderwerkinc.com/five-common-questions-about-roller-compaction-dry-granulation/

    Alexandwerwerk ebook

    If you have more specific questions chat with one of our subject matter experts in granulation development work, including roller compaction, blending, milling, drying and material handling, containment, continuous manufacturing and more use this link: https://alexanderwerkinc.com/contact-us/

    Or find your local Alexanderwerk specialist using this link: https://www.alexanderwerk.com/

  6. Are you in need of more roller compaction and dry granulation capacity? Rapid roller compactor delivery program

    Comentarios desactivados en Are you in need of more roller compaction and dry granulation capacity? Rapid roller compactor delivery program

    WP 120 in Standard Execution WP 200

    Shown here are Alexanderwerk’s pharma and nutraceutical industry roller compactor and dry granulation workhorses WP120 and WP200

    If for nothing else the Covid19 crisis has brought to light a greater sense of urgency for being able to boost local production of pharma and even nutraceutical products. Some of you may be struggling to keep up with production capacity in addition to a myriad of other manpower, supply chain, and logistics challenges.

    One area where Alexanderwerk can assist you is with our rapid delivery program. Please see here Alexanderwerk rapid delivery inventory our inventory of our high quality Made in Germany roller compactors that can be at your site as fast as the freight providers can get it to you. Our technicians are able and willing to travel to your site helping commission the roller compactor and then also train your operators and maintenance folks so you can add more dry granulation capacity to your operation in record time.

    Quality and performance of Alexanderwerk’s WP120 and 200 Pharma series roller compactors https://alexanderwerkinc.com/products/roller-compaction-pharmaceutical/ is legendary. Small size batches, up to 400Kg/hr production runs, and even continuous production is possible with the models Alexanderwerk has available. Remote trouble shooting is built into the controls come in handy when you are in a bind in today’s environment of complicated travel restrictions.

    Do not hesitate to get in touch with one of our experts using our Contact Us page https://alexanderwerkinc.com/contact-us/ or simply drop us a note at Compaction-AW@alexanderwerkinc.com

    Not located in our geographic region, but you are looking for a rapid delivery for your plant? Check out your local representative here https://alexanderwerkinc.com/

  7. Powder and Bulk Engineering article published: Maintaining powder blend content homogeneity using dry granulation

    Comentarios desactivados en Powder and Bulk Engineering article published: Maintaining powder blend content homogeneity using dry granulation

    AW regional sales managers Al Friedrich and Matt Walczer

    Albin Friedrich & Matt Walczer introduce our WP 200 Pharma during last years Granulation Seminar at our US facility.

    Our colleagues Albin “Al” Friedrich and Matt Walczer, both National Sales Managers at Alexanderwerk Inc. (USA),  recently wrote an article about how a roller compactor can be configured to properly and consistently provide a homogeneous powder blend during the granulation process. Additionally, the article covered in more detail how internal tests conducted on a WP 200 Pharma at Alexanderwerk in Montgomeryville (USA) were used to help recycle fines screened out during the granulation process and re-introduced during the compaction process.

    Alexanderwerk has a very attractive and patented solution that features a metered material flow back into its CombiVent chamber in the roller compactor’s feed hopper. Reintroducing off-size recycled granules using such a dual chamber feed hopper design delivers efficient mixing and homogeneous distribution during the granulation process. Check out the results in this article in the latest version of Powder Bulk Engineering (page 35): https://www.e-digitaleditions.com/i/1263839-pbe0720/35?

    Do you want to learn more about how to best recycled fines in your granulation process? You can either contact us via email (compaction-AW(at)alexanderwerkinc.com) or look up your local contact in our global contacts section.

    Our customers in North America can directly schedule a call with our experts in the USA and LATAM: https://tinyurl.com/ybsqkc9m

     

  8. Schedule a call (in Spanish) with an Alexanderwerk roller compaction and dry granulation expert – now also for the LATAM region

    Comentarios desactivados en Schedule a call (in Spanish) with an Alexanderwerk roller compaction and dry granulation expert – now also for the LATAM region

    Schedule a call spanish

    In these challenging times of COVID19 getting together in person has become very difficult on a good day. Businesses had to adapt and Alexanderwerk is no exception. Our Schedule a Call with a roller compaction and dry granulation expert has been very popular and it made us think about the LATAM regions that could benefit from Alexanderwerk’s roller compaction and granulation solutions for the pharmaceutical, chemical, and food industry solutions where it may be even more difficult to get together with our regional area sales manager Santiago Candela.

    His office is located in Columbia and he is ready to help you and any roller compaction and dry granulation questions in Spanish. You can use the Schedule a Call tool on the Contact Us page and you will be able to book your appointment right to your and his calendar with either a link to Zoom or MS Teams. Voila!

    Santiago is eager to help you solve your toughest compaction and granulation challenges. He has a lab in either Montgomeryville PA USA or in Remscheid at his disposal to help you test run your materials to address your specific granulation needs.

    You do not have to wait for the COVID crisis to be over in order to make progress with your specific project. Schedule your meeting with Santiago now https://alexanderwerkinc.com/es/contact-us/

    Find your global contacts right here: https://www.alexanderwerk.com/

  9. Do you have a roller compaction or granulation question? Schedule-a-call tool released

    Comentarios desactivados en Do you have a roller compaction or granulation question? Schedule-a-call tool released

    Contact us schedule a call

    Our CEO Dr. Alexander Schmidt always says it best: “We aspire to be the compaction and granulation buddy from next door – we are a compaction family” We love to collaborate with our customers. In order to make it even easier to do that we have deployed a “Schedule a Call” tool right on our Contact Us web page.

    Do you find your own lab and R&D to be behind schedule? Do you have a granulation challenge, e.g. bulk density, PSD particle size distribution, or a specific shape you want to achieve? Do you have a challenging material, e.g. fumed silica, CBD, isolate, etc? Do you have an issue with fines in your granulate? Do you want to upscale production? Do you need a specific operator protection and product containment system? Are you in need of a rental machine? There may be countless other reasons for you needing to speak with a dry roller compaction and granulation specialist.

    Here you can schedule either a 15 minute discovery talk, or even a lunch-and-learn event. Both will schedule the time with your key Alexanderwerk subject matter specialist and a calendar appointment will automatically be sent your way. Wait no longer and schedule your call now.

    We welcome you to our compaction family.

    Alexanderwerk

    PS: We are also ready to collaborate with you elsewhere in the world https://www.alexanderwerk.com/company/locations/  https://www.alexanderwerk.com/contact/global-contacts/

    https://alexanderwerkinc.com/contact-us/

  10. Issues with poor flowing CBD Isolate? We can solve that!

    Comentarios desactivados en Issues with poor flowing CBD Isolate? We can solve that!

    Typical CBD isolate material (powder) has poor flow characteristics and is usually light and fluffy.  This unfortunate property makes it difficult to handle and especially challenging when feeding the material to downstream blending operation or a tablet press. Luckily, this challenge is easy to solve, by converting the small fine powder into a larger flowing granule – all without altering the chemical properties of the isolate.  Welcome to dry granulation technology.

    Dry granulation by roller compaction is a well-established process in pharmaceutical, chemical and life science industry. In pharmaceutical applications, the most common target is to increase the flowability of a powder or powder blend to enable the fast and homogeneous filling of a tablet press. The challenge is to produce tablets of constant weight and sufficient strength, while maintaining an even distribution of the Active Pharmaceutical Ingredients (API), or in this case, the CBD Isolate powder. This can be achieved by roller compaction for a wide range of products and without the need of additional ingredients such as binders, moisture or lubricants. Furthermore, dry granulation by roller compaction is used to eliminate dust, increase the bulk density, reduce the storage volume, improve handling and manipulate the dissolution properties.

    Dry granulation by roller compaction consists of two separate steps. The first step is an agglomeration step, starting From Raw Material Powder to a Flake. The second step is a size reduction step, From Flake to Granulate. Here the flake is milled and reduced to a good flowing granulate by using a Flake Crusher, Pre- and Fine-Granulator. A Detailed view on a Roller Compactor can be seen in Figure 1 and the flow diagram can be seen in Figure 2. You can find a helpful decision making guideline and granulation process video here: https://alexanderwerkinc.com/products/roller-compaction-pharmaceutical/

    Detailed view on a roller compactor                            Flow diagram of a roller compactor

    Figure 1:Detailed view on a Roller Compactor                            Figure 2: Flow Diagram of a Roller Compactor

     

    Are you curious about what dramatically improving flowability may look like? Check out our YouTube video that shows you the before and after granulation effect of roller compaction: https://www.youtube.com/watch?v=vk0JPwnzylg&t=2s

     

    We love solving complex compaction and granulation challenges. Please reach out to us:  https://alexanderwerkinc.com/contact-us/

    Please also check out our global representation here: www.alexanderwerk.com

     

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