What You Should Know About Granulation Solutions for Nutraceuticals Manufacturing

Backed by more than 130 years of experience, Alexanderwerk has established itself as a world leader in the production of compaction and granulation machines. With the latest technology, we serve our clients in the nutraceutical, pharmaceutical, CBD, food, chemical, & life sciences. In addition to new equipment sales, we offer machinery rentals and laboratory testing services.

With the recent growth in the health and wellness industry, particularly in the wake of COVID-19, comes an increased demand for nutraceuticals manufacturing. Nutraceuticals, including supplements and functional foods, are typically made from plants and animals and are used to treat and prevent illnesses. This industry is on the rise, with the global market expected to soar over the next decade. 

What is a Nutraceutical?

The word “nutraceutical” is a term covering a broad selection of products that promote general good health and wellbeing. Some of the most common examples of nutraceuticals would include vitamins and probiotics, though the category covers a much broader term of supplements.

Nutraceutical vs. Pharmaceutical

Of note, nutraceuticals and pharmaceuticals are not the same thing. Some of the primary differences between these two products include:

• Production volumes. Unlike pharmaceuticals, which are mass produced in high volumes for global distribution, nutraceuticals are often produced by small start-ups and in proof-of-concept quantities, or in mid-level production volumes. 
• Availability. While pharmaceuticals require a prescription from a licensed medical professional, nutraceuticals are available to consumers over the counter.
• Lifecycle. Nutraceuticals have a much faster speed-to-market compared to pharmaceuticals for a variety of reasons. Nutraceuticals tend to have much shorter production cycles, for starters. Additionally, pharmaceuticals require FDA approval, which can hold up product launches for years.

Solutions for Powder Material Flow

Pharmaceutical and nutraceutical companies ultimately have the same production goal—developing a production process that allows them to get products to their end users more efficiently. Material flow processes often represent one of the largest roadblocks for manufacturing this type of product. 

Alexanderwerk offers machines that facilitate efficient powder flow during the production of tablets and capsules. Powder flow is an essential component in successful nutraceutical and pharmaceutical manufacturing. Efficient powder flow can impact numerous factors, including:

• Production speed. Without proper powder flow, tablet presses may run significantly slower than expected.
• Calidad. Reliable powder flow helps to ensure accuracy and consistency in dosage and weight across all tablets in the production run. 
• Blending. Blending multiple powdered components relies heavily on efficient powder flow.

While some aspects of powder flow depend on the quality of the powdered material itself and the way in which it was stored, effective powder flow in nutraceutical manufacturing ultimately relies on using reliable, high-performance equipment. 

Premium Lab Services & Equipment Rentals for Nutraceutical Manufacturing

Working with us can simplify the process of getting your nutraceuticals to market. Our technology helps users achieve compliance by enabling them to produce consistent product quality in equipment that is designed to meet cGMP and pharmaceutical design standards. You can add the product to your lineup without interrupting or rearranging your current production schedule and without having to expand your facility. 

Alexanderwerk produces leading-edge compaction and granulation machinery. We serve companies of all sized companies who would like to bring a nutraceutical to market. We also offer a variety of supplementary services:

• Test Lab. Experiment with our equipment to see what’s possible or supplement your capabilities.
• Compaction Equipment Rental. For proof of concept testing or producing material for a clinical trial, renting the equipment is a cost-effective way to get started on an experimental project before investing in your own machinery. 

At Alexanderwerk, we’re committed to improving your production process and eliminating bottlenecks and productivity challenges with the latest technology. For more information, download our e-books, or you can contáctenos any time to request a quote. 

Alexanderwerk exhibits in person at the Interphex show 2021 taking place at the Javits Center in New York City (USA) from October 19 – 21

Come on our and stop by at Booth #2465. Our regional sales managers Albin Friedrich and Matt Walczer are looking forward to seeing you there. You can familiarize yourself with our roller compaction and dry granulation technology. Put the odds in your favor and speak to them about your material processing needs. They have extensive material processing know-how and you can get the latest insights into Dry Granulation, Roller Compaction, Shredding, Grating and Milling!

For more information or personal appointments, please contact our colleagues from Alexanderwerk Inc. Matt Walczer and Al Friedrich and set up a meeting time that will work for you.

Direct link to the registration for the show – Visitor Registration.

Website of the organizers: Interphex 2021

See you there!

Alexanderwerk supports premier hands-on training in Telford (Pennsylvania, USA) in October

Our partners Natoli Scientific and TechCeuticals will hold a 2.5-day-seminar on “Tablet Compression Research & Development” and our experts from Alexanderwerk Inc. will support this premier hands-on training event. The seminar will take place at the Natoli Lab in Telford (October 5-7, 2021). Hurry up to get registered for this event as seats are limited. Early bird registration ends on September 25th.

La serie 2.5-day training course incorporates:

• Tablet & tool designs
• Micromeritics
• Tablet compression with scale-up
• Granulation (roller compaction, high shear, fluid bed)
• Milling techniques
• Hot melt extrusion
• Excipient functionality & selection
• Formulation development strategies

This course is designed for those involved in tablet compression Research & Development including:

• Compounding Pharmacists
• Technology Transfer Scientists
• Process and Validation Engineers
• Formulation Scientists
• Research Associates
• Manufacturing professionals
• Quality & Regulatory

The organizer’s website can be reached here. Please contact Natoli’s team for further requirements due to Covid-19 and implemented hygienic concepts.

A flyer for the seminar can be downloaded from Natoli’s website.

Following companies will present during the seminar:

• Alexanderwerk
• Frewitt
• Federal Equipment
• Glatt
• JRS Pharma
• Natoli
• TechCeuticals

Alexanderwerk will exhibit at the Powder & Bulk Solids Conference and Exhibition 2021 taking place at the Donald E. Stephens Convention Center in Rosemont, Illinois (USA) from August 24 – 26, 2021.

Alexanderwerk will exhibit at the Powder & Bulk Solids Conference and Exhibition 2021 taking place at the Donald E. Stephens Convention Center in Rosemont, Illinois (USA) from August 24 – 26, 2021.

Come on our and stop by at Booth #2505. Our regional sales managers Albin Friedrich and Matt Walczer are looking forward to collaborate with you. Besides being able to introduce you to our dry granulation technology with roller compactors you can talk to them about your material processing needs.  Don’t miss it and get the latest insights into Dry Granulation, Roller Compaction, Shredding, Grating and Milling!

For more information or personal appointments, please contact our colleagues from Alexanderwerk Inc. (contact person: Matt Walczer).

Direct link to the registration for the show – Visitor Registration.

Website of the organizers: PBS2021

#alexanderwerk #drygranulation #rollercompaction #pbs2021

Alexanderwerk Inc will exhibit at the in-person CPhI 2021 show in Philadelphia August 10-12, 2021

We are so happy that we will be able to greet you live at this year’s CPhI in Philadelphia. Come on out to meet with our #rollercompaction and #drygranulation experts Al Friedrich and Matt Walczer in our booth 1224. They are ready to collaborate with you helping solve your material, process and containment challenges.

Make sure to make your reservation soon. Here is the link to get your pass from the show organizer: https://tinyurl.com/2wpbdtfy

Are you busy and you would like to maximize your time walking the show floor? We can help you with that. If you have a specific time slot that fits your calendar you may want to reserve a time using Al’s https://tinyurl.com/dfm88cjv and Matt’s https://tinyurl.com/327zara3 scheduling tool links.

#pharma #pharmaindustry #pharmaceuticalmanufacturing #pharmaceuticalindustry #alexanderwerk

Alexanderwerk Inc installs more efficient LED lighting

Alexanderwerk’s dry roller compaction and granulation machines have a solid reputation for being energy efficient, reliable, and having very low overall life cycle costs. In addition to that, this technology is reported to use 10-15% of the energy of the alternative wet granulation technology. Our company prides itself with striving toward a goal of greater long term sustainability. Alexanderwerk has a long term sustainability strategy striving to lower the impact on our resources and the environment. At Alexanderwerk Inc we have already deployed a variety of sustainability measures:

• None of our trash ends up in the landfill. Instead it is turned into energy by our waste and recycling company.
• We recycle all cardboard, shipping materials, and of course all other standard recyclable materials.
• We are pay close attention to minimizing waste water generation and capturing and then disposing of such in a responsible manner.
• We feature a state of the art lab air treatment system that captures particulate so that it does not spread around our facility.
• We follow Lean Manufacturing principles and are continually improving our value streams.
• We strive to become a completely paperless organization.
• We offer remote office work helping reduce commuting and thus lower carbon emissions.

Alexanderwerk Inc just recently audited its own energy usage. One major energy consuming line item was identified to be the fluorescent and HID lighting in office and warehouse. On average the newly installed LED lighting consumes an impressive 1/3 energy of the originally installed fluorescent and HID lighting. In addition to conserving energy the employees as well as visiting customers can now enjoy a much brighter and natural light like atmosphere – and we have become more environmentally friendly as well.

Photo: Krista Stapf, Estimator from PECO ally Centrica and Ralf Weiser, VP of Operations

 Alexanderwerk exhibits at the Expo Virtual Alemania Latinoamerica (July 6 – 9, 2021)

The team from Alexanderwerk Colombia, located in Bogota, has been looking after our customers in the LATAM region since 2019. As part of our local cooperation with the AHK Colombia, we will take part in the Expo Virtual Alemania Latinoamerica this year. Our branch will be present at the fair from July 6th to 9th, 2021.

Our Bogota based colleague Santiago Candela, National Sales Engineer for the LATAM region

You can obtain information about the trade fair from the organizer’s website, which also can be used for the visitor registration.

20 countries take part in the fair and products from Germany and the LATAM region are presented. Exhibitors from 10 productive sectors look forward to your visit – be there!

Also, don’t miss the daily conferences that take place in parallel with the fair.

You will find our virtual booth under this link opening on July 6th.

Alexanderwerk expone en la Expo Virtual Alemania Latinoamérica (del 6 al 9 de julio de 2021)

El equipo de Alexanderwerk Colombia, ubicado en Bogotá, atiende a nuestros clientes en la región de LATAM desde 2019. Como parte de nuestra cooperación local con la AHK Colombia, este año participaremos en la Expo Virtual Alemania Latinoamérica. Nuestra sucursal estará presente en la feria del 6 al 9 de julio de 2021.

Puede obtener información sobre la feria en el sitio web del organizador, que también puede utilizarse para el registro de visitantes.

En la feria participan 20 países y se presentan productos de Alemania y de la región LATAM. Expositores de 10 sectores productivos esperan su visita – ¡no falte!

Además, no se pierda las conferencias diarias que tienen lugar en paralelo a la feria.

Encontrará nuestro stand virtual en este enlace que se abrirá el 6 de julio.

Alexanderwerk helped support Natoli’s Tableting and Dry Granulation Techniques Webinar Session II

Natoli and Alexanderwerk partnered in Session II of this recent webinar. A comparative study using 3 levels of Acetaminophen active in a tablet formulation provided the scientific backdrop of this session. Powder flow, compactability and scalability was evaluated utilizing Natoli’s products and services. Our own Al Friedrich covered Alexanderwerk’s dry granulation roller compaction technology while Natoli’s Rob Sedlock expanded on tableting fundamentals.

Did you miss this webinar? Not to worry, please find below the link to this video which is packed with useful information. If you are working in the pharmaceutical OSD development and / or manufacturing realm this video is for you. https://www.youtube.com/watch?v=p0IiPgCmlIc

Alexanderwerk supports premier hands-on training in Cleveland (Ohio, USA) in July

Our partners Natoli Scientific and TechCeuticals will hold a 2-day-seminar on “tablet compression research & development” and our experts from Alexanderwerk Inc. will support this premier hands-on training event. The seminar will take place at the TechCeuticals Lab in Cleveland (July 20 – 21, 2021). Hurry up to get registered for this event as seats are limited and an early-bird-rate is available only until June, 25th!

La serie 2-day training course incorporates:

• Tablet & tool designs
• Micromeritics
• Tablet compression with scale-up
• Granulation (roller compaction, high shear, fluid bed)
• Milling techniques
• Hot melt extrusion
• Excipient functionality & selection
• Formulation development strategies

This course is designed for those involved in tablet compression Research & Development including:

• Compounding Pharmacists
• Technology Transfer Scientists
• Process and Validation Engineers
• Formulation Scientists
• Research Associates
• Manufacturing professionals
• Quality & Regulatory

The organizer’s website can be reached here. Please contact Natoli’s team for further requirements due to Covid-19 and implemented hygienic concepts.

A flyer for the seminar can be downloaded from Natoli’s website

Following companies will present during the seminar:

• Alexanderwerk
• Frewitt
• Federal Equipment
• Glatt
• JRS Pharma
• Natoli
• TechCeuticals
• ThermoFisher Scientific

NATOLI-Techceuticals-Hands-On-Training-2021-Brochure

First impressions from CIPM 2021 in QingDao (P.R. China)

Alexanderwerk exhibits at the 60th China International Pharmaceutical Machinery Exposition 5/10/2021 – 5/12/2021

Alexanderwerk is happy to have a base in Shanghai helping support our numerous partners and customers in China. Hence, it was no question for us at all to join this year’s CIPM in QingDao.

See some impressions from our booth N5-26 and feel free to visit us in QingDao. Our colleagues will be very happy to introduce you to the advantages of Dry Granulation and the Alexanderwerk portfolio.

CIPM is a large pharmaceutical machinery industry show held in China since 1991. It has been held since 1991.