Do you have a roller compaction or granulation question? Schedule-a-call tool released

Our CEO Dr. Alexander Schmidt always says it best: “We aspire to be the compaction and granulation buddy from next door – we are a compaction family” We love to collaborate with our customers. In order to make it even easier to do that we have deployed a “Schedule a Call” tool right on our Contact Us web page.

Do you find your own lab and R&D to be behind schedule? Do you have a granulation challenge, e.g. bulk density, PSD particle size distribution, or a specific shape you want to achieve? Do you have a challenging material, e.g. fumed silica, CBD, isolate, etc? Do you have an issue with fines in your granulate? Do you want to upscale production? Do you need a specific operator protection and product containment system? Are you in need of a rental machine? There may be countless other reasons for you needing to speak with a dry roller compaction and granulation specialist.

Here you can schedule either a 15 minute discovery talk, or even a lunch-and-learn event. Both will schedule the time with your key Alexanderwerk subject matter specialist and a calendar appointment will automatically be sent your way. Wait no longer and schedule your call now.

We welcome you to our compaction family.

Alexanderwerk

PS: We are also ready to collaborate with you elsewhere in the world https://www.alexanderwerk.com/company/locations/  https://www.alexanderwerk.com/contact/global-contacts/

https://alexanderwerkinc.com/contact-us/

Issues with poor flowing CBD Isolate? We can solve that!

Typical CBD isolate material (powder) has poor flow characteristics and is usually light and fluffy.  This unfortunate property makes it difficult to handle and especially challenging when feeding the material to downstream blending operation or a tablet press. Luckily, this challenge is easy to solve, by converting the small fine powder into a larger flowing granule – all without altering the chemical properties of the isolate.  Welcome to dry granulation technology.

Dry granulation by roller compaction is a well-established process in pharmaceutical, chemical and life science industry. In pharmaceutical applications, the most common target is to increase the flowability of a powder or powder blend to enable the fast and homogeneous filling of a tablet press. The challenge is to produce tablets of constant weight and sufficient strength, while maintaining an even distribution of the Active Pharmaceutical Ingredients (API), or in this case, the CBD Isolate powder. This can be achieved by roller compaction for a wide range of products and without the need of additional ingredients such as binders, moisture or lubricants. Furthermore, dry granulation by roller compaction is used to eliminate dust, increase the bulk density, reduce the storage volume, improve handling and manipulate the dissolution properties.

Dry granulation by roller compaction consists of two separate steps. The first step is an agglomeration step, starting From Raw Material Powder to a Flake. The second step is a size reduction step, From Flake to Granulate. Here the flake is milled and reduced to a good flowing granulate by using a Flake Crusher, Pre- and Fine-Granulator. A Detailed view on a Roller Compactor can be seen in Figure 1 and the flow diagram can be seen in Figure 2. You can find a helpful decision making guideline and granulation process video here: https://alexanderwerkinc.com/products/roller-compaction-pharmaceutical/

Figure 1:Detailed view on a Roller Compactor                            Figure 2: Flow Diagram of a Roller Compactor

Are you curious about what dramatically improving flowability may look like? Check out our YouTube video that shows you the before and after granulation effect of roller compaction: https://www.youtube.com/watch?v=vk0JPwnzylg&t=2s

We love solving complex compaction and granulation challenges. Please reach out to us:  https://alexanderwerkinc.com/contact-us/

Please also check out our global representation here: www.alexanderwerk.com

Powder and Bulk Engineering article published: Maintaining powder blend content homogeneity using dry granulation

Matt Walczer and Al Friedrich from Alexanderwerk Inc

Our Al Friedrich and Matt Walczer recently wrote an article about how a roller compactor can be configured to properly and consistently provide a homogeneous powder blend during the granulation process. Additionally, the article covered in more detail how internal tests conducted at Alexanderwerk were used to help recycle fines screened out during the granulation process and re-introduced during the compaction process.

Alexanderwerk has a very attractive solution that features a metered material flow back into its CombiVent chamber in the roller compactor’s feed hopper. Reintroducing off-size recycled granules using such a dual chamber feed hopper design delivers efficient mixing and homogeneous distribution during the granulation process. Check out the results in this article in the latest version of Powder Bulk Engineering here on page 35: https://tinyurl.com/y9582rch

Do you want to learn more about how to best recycled fines in your granulation process? Click here to schedule a call with one of our experts: https://tinyurl.com/ybsqkc9m